Greater fatigue can instigate pathways in the muscle cells that essentially lead to higher muscle protein synthesis, particularly when ample protein is available. High reps essentially create more waste products in muscle fibers, which is due to greater muscle fatigue. This stretch not only makes muscles momentarily bigger, but it also initiates biochemical pathways that signal the muscle cell to grow.Training with high reps causes a greater flow of blood to the trained muscles the muscle contractions stimulate blood to move in that direction. The pump essentially places a stretch on the muscle cell. These waste products are the result of burning glucose and fat to fuel muscle contractions, and their build-up inside muscle cells draws water in from blood in the capillaries that feed the muscle and the area surrounding the cells.As with a balloon, the more water the muscle cell can hold, the bigger the pump. When you train, you produce waste products in the muscle cells. Simply put, the pump is the filling up of muscle cells with water. The pump is the rapid expansion in the size of muscles during a workout.
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